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Home Therapy Infections in HIV / cellular immune disorders

pneumocystis jirovecii pneumonie

Advices

≥ 18 years
Priority Medication Remarks
Medication:

cotrimoxazol (trimethoprim + sulfamethoxazol) iv 1920mg 3dd 14 days
Remarks:

SWAB remarks

milde gevallen evt. per os

UMCG remarks

  • NB: Bij HIV patiënten duur therapie 21 dagen
Medication:

cotrimoxazol (trimethoprim + sulfamethoxazol) iv 1440mg 3dd 14 days
Remarks:

SWAB remarks

gewicht < 50 kg

milde gevallen evt. per os
Medication:

trimethoprim po 300mg 3dd 21 days

+

dapsone po 100mg 1dd 21 days
Remarks:

SWAB remarks

overgevoeligheid co-trimoxazol
Medication:

clindamycine iv 600mg 3dd 21 days

+

primaquine po 30mg 1dd 21 days
Remarks:

SWAB remarks

overgevoeligheid co-trimoxazol
Medication:

atovaquon po 750mg 2dd 21 days
Remarks:

SWAB remarks

suspensie, innemen met voedsel; alleen bij niet ernstige PCP
Medication:

pentamidine iv 4mg/kg 1dd 21 days
Remarks:

SWAB remarks

laatste lijn

General comments

Bij pO2 < 70 mm Hg of 8-9 kPa toevoegen prednisolon:

  • dag 1-5: 2 dd 40 mg;
  • dag 6-10: 1 dd 40 mg;
  • dag 11-14: 1 dd 20 mg.

Na behandeling secundaire profylaxe.

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-8292.5
Updated: 11/28/2023 - 16:18
Status: Published